A clinical-stage biopharmaceutical company announced that it has commenced dosing in a Phase 1 single ascending dose (SAD) and multiple ascending dose (MAD) clinical study of ALT-801.
Altimmune, Inc. stated in a press release that ‘ALT-801 is a long-acting GLP-1/glucagon receptor dual agonist being developed for the treatment of non-alcoholic steatohepatitis (NASH), which is expected to affect more than 13 million adults in the USA.’
Innovative Peptide Study Evaluates Reduction in Liver Fat and Increased Weight Loss
Positive In vitro Efficacy Data for Nasal Spray Protecting Against Coronavirus Infection
A Bermuda based clinical-stage company announced positive efficacy data from testing AM-301 nasal spray in vitro against a SARS-COV-2 coronavirus infection.
This study by Auris Medical Holding Ltd. reported up to 99.4 percent reduction of viral titer in human epithelial cell culture.
Oxford COVID-19 Vaccine Found Adults Protected Against Disease
The Lancet published peer-reviewed, interim results of the Oxford COVID-19 vaccine (AZD1222) studies find that the vaccine protects against symptomatic disease in 70 percent of cases, with vaccine efficacy (VE) of 62 percent for those given 2 full doses.
Additionally, The Lancet disclosed on December 8, 2020, the VE was reported at 90 percent in those participants given a half, then a full dose (both trial arms pre-specified in the pooled analysis).
Large U.S. Claims Study IDs Complications of COVID-19
Association with COVID-19 strong, absolute risk high for viral pneumonia, respiratory failure, acute kidney failure, sepsis
Hep C Testing, Identification Plummet During COVID-19
Reductions seen in hospital-wide and ambulatory clinic HCV testing, identification of new HCV+ patients
Pediatric Appendiceal Perforation Up During COVID-19 Pandemic
Delays in medical care attributable to COVID-19 may cause additional morbidity in children
Masks Containing Metal Could Cause Burns During MRI, FDA Warns
Metal parts include bendable nose clips, staples on the headband, nanoparticles, or antimicrobial coating
FDA Review Finds Pfizer COVID-19 Vaccine Effective After First Dose
Vaccine is expected to receive emergency use authorization later this week
Mystery Illness Strikes Hundreds in India
Symptoms similar to those associated with epilepsy, including headaches, nausea, vomiting, seizures
California Introduces Smartphone Coronavirus Exposure Alert Tool
If a user tests positive for COVID-19, they will receive a code they can use to send an anonymous alert to others