Sanofi and GSK announce a delay in their adjuvanted recombinant protein-based COVID-19 vaccine program to improve immune response in older adults.
This decision was published on December 11, 2020, and was based on the Phase 1/2 study interim results which showed an immune response comparable to patients who recovered from COVID-19 in adults aged 18 to 49 years.
But, a low immune response in older adults, likely due to an insufficient concentration of the antigen, stated the companies.
Protein-Based COVID-19 Vaccine Candidate Delays Advanced Research
New Polio Vaccines Display Good Immune Response Against Mutated Strain
Clinical studies indicate the new poliovirus vaccine may have the potential to overcome outbreaks caused by a mutated polio strain linked to the oral vaccine.
According to studies published by The Lancet on December 9, 2020, scientists have developed the first poliovirus vaccine against a mutated form of the disease that is causing disease outbreaks across Africa and Asia.
Australian COVID-19 Vaccine Candidate Cancels Clinical Trial
The University of Queensland announced that following consultation with the Australian Government, CSL will not progress the UQ-CSL v451 COVID-19 vaccine candidate to Phase 2/3 clinical trials.
Oxford and AstraZeneca To Test Sputnik V Vaccine’s Components
The Russian Direct Investment Fund (RDIF) and the N.F. Gamaleya Research Center announced AstraZeneca has accepted the RDIF proposal and will begin clinical trials of its vaccine in combination with the Sputnik V adenoviral vector of the 26th serotype, by the end of 2020.
70 Percent Efficacy Found for Oxford COVID-19 Vaccine
Acceptable safety profile identified, with three serious adverse events classified as possibly related to the vaccine
Essential Workers Have Increased Risk for Severe COVID-19
Highest risk for testing positive or death due to COVID-19 was seen for non-White essential workers
Hyposmia, Dysgeusia Common for Patients With COVID-19
Total leukocyte and neutrophil counts lower among patients with hyposmia
Drop in ED Visits Related to Child Abuse, Neglect During COVID-19
Decrease in total number of ED visits versus corresponding 2019 period, but proportion of these visits increased
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of Dec. 7 to 11, 2020. This …
- Page 1 of 2
- 1
- 2