A Phase 1 clinical trial featuring an investigational vaccine that uses a person’s own immune cells, a beta cell protein, and vitamin D3 to potentially treat type 1 diabetes is now recruiting patients.
The City of Hope trial is part of The Wanek Family Project for Type 1 Diabetes, which seeks to find cures for the disease.
Known as the PIpepTolDC vaccine, the “inverse” vaccine, which was previously evaluated for safety and feasibility in a clinical trial in the Netherlands. An inverse vaccine aims to stop certain specific immune responses rather than activate them.
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