A large clinical trial of people living with HIV has found that treating anal precancerous growths known as high-grade squamous intraepithelial lesions (HSIL) reduces the chance that anal cancer will develop by over 50%.
Nearly all cases of anal cancer are caused by infection of anal cells with cancer-causing types of human papillomavirus (HPV).
Although HPV vaccination can prevent new anal HPV infections, no evidence-based recommendations are currently available to guide screening for and treating anal HSIL.
HPV Vaccinations Can Prevent Anal Cancer
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