Local and systemic reactions reported less frequently after fourth dose versus dose 3 of primary vaccination series
Immunocompromised Hospitalized With COVID-19 Have Poor Outcomes
Immunocompromised patients have increased odds of ICU admission, in-hospital death, regardless of vaccination status
Scientists Report ‘Rogue Antibodies’ Behind Severe Clotting With COVID-19
Study authors suggest future research assess the potential benefits of screening COVID-19 patients for antiphospholipids and other autoantibodies
Breakthrough COVID-19 Infection Risk Higher With Immune Dysfunction
Risk for breakthrough infection higher for those with immunocompromising conditions, such as HIV, rheumatoid arthritis, solid organ transplant
COVID-19 Breakthrough Infections More Common in Immunocompromised Patients
Immunocompromised patients accounted for 38.2 percent of breakthrough infections
Most Immunosuppressive Meds Not Tied to Worse COVID-19 Outcomes
Except for rituximab, no increased risk seen for in-hospital death or mechanical ventilation for those on long-term immunosuppressive therapy
mRNA COVID-19 Efficacy Lower for Immunocompromised Adults
Vaccine effectiveness of two doses of mRNA vaccine lower against COVID-19-associated hospitalization, with variation by condition
Immunocompromised May Need Fourth COVID-19 Shot: CDC
Small studies have shown that fully vaccinated immunocompromised people account for ~44 percent of breakthrough cases leading to hospitalization
FDA OKs Third COVID-19 Shot for Vulnerable Americans
Authorization includes people who have had solid organ transplants and those whose immune systems are equally compromised
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