A Pennsylvania based biotechnology company announced positive efficacy results for an open-label Phase 2 trial of VGX-3100 to treat HPV-16 and HPV-18-associated vulvar dysplasia.
A 25 percent or more reduction in HPV-16/18-associated vulvar HSIL (high-grade squamous intraepithelial lesion) was observed for 63 percent of trial participants (12 of 19) treated with VGX-3100 at six months post-treatment, stated INOVIO Pharmacuticals, Inc.’s press release issued on January 6, 2021.
HPV Treatment Demonstrates Positive Phase 2 Efficacy When Treating Precancerous Vulvar Dysplasia
WHO Grants Prequalification of Sabin-IPV Polio Vaccine
South Korean-based biotechnology company announced that its Sabin-Inactivated Polio Vaccine (Sabin-IPV) Eupolio™ is the first to receive the World Health Organization (WHO) prequalification be supplied globally.
LG Chem stated in a press release, ‘Eupolio demonstrated excellent phase III results in 2019, inducing high antibody titers against both wild-type and Sabin polioviruses, which will also protect against circulating vaccine-derived polioviruses (cVDPV) that make up the majority of polio cases in recent years.’
Majority of SARS-CoV-2 Transmission Due to Asymptomatic Individuals
In base case of modeling study, 59 percent of transmission attributed to presymptomatic and asymptomatic individuals
Red Cross Issues Call for More Blood Plasma to Treat COVID-19 Patients
People who have recovered from COVID-19 may have antibodies in their plasma that could boost immunity in current patients
Allergists Affirm Safety of COVID-19 Vaccines for Most
All patients should be observed for 15 minutes after vaccination; staff should be trained in anaphylaxis management
11.1 Anaphylaxis Cases/Million Doses of Pfizer-BioNTech COVID-19 Vaccine Reported
Median interval from vaccine receipt to symptom onset was 13 minutes
Mental Well-Being Worse for Men From Ethnic Minorities During Pandemic
Greater average increase in mental distress during COVID-19 seen for women and for Black, Asian, minority ethnic versus White British men
NFL Urges Teams to Offer Stadiums as Vaccination Centers
NFL would benefit from Americans being vaccinated because it increases the odds that state officials will reopen stadiums
Collaboration Launches to Assess the Prevalence of Coronavirus Variant
A collaboration agreement to augment national surveillance infrastructure in the USA to track the emergence and prevalence of novel strains of SARS-CoV-2 was announced.
With support from the US Centers for Disease Control and Prevention (CDC), llumina, Inc., and Helix announced the combination of sequencing technology, expertise, and a national COVID-19 testing footprint would significantly expand the USA’s existing surveillance efforts to detect and characterize emerging variants of the SARS-CoV-2 betacoronavirus.
Psychological Distress Increased in U.S. During COVID-19
Numbers of people who experienced serious psychological distress over 30 days during pandemic similar to that in entire year prior to pandemic