A recently published review aimed to assess the necessity of a booster vaccination based on the long-term immunogenicity of primary yellow fever vaccination.
Overall, these researchers found that most primary vaccine recipients maintain neutralizing antibodies above protective thresholds ten or more years post-vaccination.
In healthy adults in non-endemic settings, who were primarily travelers, this systematic review and meta-analysis observed high rates of seroprotection 10–60 years post-vaccination (overall seroprotection rate 94%).
Are Yellow Fever Vaccine Boosters Needed
Updated COVID-19 Vaccine Has Effectiveness of 54 Percent
Vaccine effectiveness 49 percent at 60 to 119 days after vaccination among tests exhibiting spike gene target failure