Females underrepresented in treatment trials, while Asian, Black participants underrepresented in prevention trials
Preprint, Peer-Reviewed Pairs of Studies Generally Concordant
Sample sizes, primary end points, interpretations mainly concordant for studies published on medRxiv, then in journals
FDA Oversight of Clinical Trials Described as ‘Grossly Inadequate’
Article describes inadequate oversight relating to development of COVID-19 vaccines and predating the pandemic
NIH Investigating COVID-19 Experiments Conducted at Boston University
WEDNESDAY, Oct. 19, 2022 (HealthDay News) — The U.S. National Institutes of Health is investigating COVID-19 experiments at Boston University that have sparked a media firestorm, with some news outlets …
Disruption to Oncology Clinical Trials Seen Early in Pandemic
Numbers of new patient accruals and newly activated trials decreased early on, followed by progressive recovery
Another HIV Vaccine Trial Canceled Due to Poor Results
Cancellation is the latest in a string of failures for HIV vaccine research
Enrollment in Cancer Treatment Trials Largely Unchanged by Pandemic
However, there was a significant decrease in enrollment for cancer control and prevention trials
Should Changes Made to Clinical Trials During Pandemic Be Kept?
Changes were recommended to preserve potential patient benefit while minimizing risks associated with COVID-19
NIH Starts Trial Assessing ‘Mix & Match’ COVID-19 Vaccine Approach
Individuals who received J&J, Moderna, or Pfizer-BioNTech vaccine will receive single booster dose of Moderna vaccine 12 to 20 weeks later
NIH Halts Trial of Convalescent Plasma for Mild COVID-19
While the treatment seemed safe, no significant differences in outcomes were seen between patients receiving convalescent plasma or placebo
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